منابع مشابه
Caspases: Intracellular Signaling by Proteolysis
Ectopic expression of caspase 1 in some cells can result The discovery of a novel proteolytic network in the cytoin apoptosis, but a role in developmentally programmed sol of metazoan cells comes as a surprise to a field that cell death is unlikely given the normal phenotype of previously considered intracellular proteolysis to mainly knockout mice (see for example, Ghayur et al., 1997). be a m...
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BACKGROUND The appropriate control of mitotic entry and exit is reliant on a series of interlocking signaling events that coordinately drive the biological processes required for accurate cell division. Overlaid onto these signals that promote orchestrated cell division are checkpoints that ensure appropriate mitotic spindle formation, a lack of DNA damage, kinetochore attachment, and that each...
متن کاملMigratory Behavior of Hunted Elk
During 1990–2000, I investigated patterns of fall migration and harvests of the Jackson elk herd. Specifically, I compared the timing of fall migration of the 2,500–4,500 elk (Cervus elaphus) that summered in Grand Teton National Park (GTNP) and wintered on the National Elk Refuge (NER) with elk that used other summer ranges by monitoring 512 migrations of radiocollared elk and by direct counts...
متن کاملHunted predators: Charisma confounds.
IN THEIR PERSPECTIVE “When the hunter becomes the hunted” (19 June, p. 1312), R. Woodroffe and S. M. Redpath rightly pointed out that a social consensus, in addition to scientific evidence, is critical to effectively control species deemed overabundant, such as some predators, because social conflicts over the need for control undermine management decisions. We stress here that social acceptabi...
متن کاملCaspases
U ncontrolled lymphoproliferation is a characteristic feature of lymphomas and leukemias. Nonmalignant lym-phoproliferative diseases are also observed in humans as well as in lpr (lymphoproliferation) and gld (generalized lymphad-enopathy) mice. The discoveries that spontaneous mutations of Fas (APO-1/CD95) or its ligand (FasL) were associated with the lpr and gld phenotypes led to a satisfying...
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ژورنال
عنوان ژورنال: Cell Death & Disease
سال: 2016
ISSN: 2041-4889
DOI: 10.1038/cddis.2016.153